Target：Synaptotagmin X
Gene Name：SYT10
Protein Name：Synaptotagmin-10
Human Gene Id：341359
Human Swiss Prot No：Q6XYQ8
Mouse Gene Id：54526
Mouse Swiss Prot No：Q9R0N4
Rat Gene Id：60567
Rat Swiss Prot No：O08625
Immunogen：Synthesized peptide derived from Synaptotagmin X . at AA range: 380-460
Specificity：Synaptotagmin X Polyclonal Antibody detects endogenous levels of Synaptotagmin X protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500-2000;IHC 1:50-300
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：SYT10;Synaptotagmin-10;Synaptotagmin X;SytX
Observed Band(KD)：55kD
Background：cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Homodimer. Can also form heterodimers.,tissue specificity:Expressed only in pancreas, lung and kidney.,
Function：cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Homodimer. Can also form heterodimers.,tissue specificity:Expressed only in pancreas, lung and kidney.,
Subcellular Location：Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein . Localizes to neuronal vesicles containing IGF1 that are not enriched at synapses. Does not colocalize with synaptic vesicles or with the Golgi apparatus. .
Expression：Expressed only in pancreas, lung and kidney.
