Target：SYN3
Gene Name：SYN3
Protein Name：Synapsin-3 (Synapsin III)
Human Gene Id：8224
Human Swiss Prot No：O14994
Mouse Swiss Prot No：Q8JZP2
Rat Swiss Prot No：O70441
Immunogen：Synthesized peptide derived from part region of human protein. AA range 530-580
Specificity：SYN3 Polyclonal Antibody detects endogenous levels of protein.
Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500-2000 ELISA 1:5000-20000
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD)：63kD
Background： This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite directi
Function：function:May be involved in the regulation of neurotransmitter release and synaptogenesis.,miscellaneous:Regulated by calcium. Calcium inhibits ATP binding to the C-domain.,similarity:Belongs to the synapsin family.,subcellular location:Peripheral membrane protein localized to the cytoplasmic surface of synaptic vesicles.,subunit:Interacts with CAPON.,tissue specificity:Neuron specific. Detected predominantly in brain.,
Subcellular Location：Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Peripheral membrane protein localized to the cytoplasmic surface of synaptic vesicles.
Expression：Neuron specific. Detected predominantly in brain.
