Target:IF3
Gene Name:MTIF3
Protein Name:Translation initiation factor IF-3 mitochondrial
Human Gene Id:219402
Human Swiss Prot No:Q9H2K0
Mouse Swiss Prot No:Q9CZD5
Immunogen:The antiserum was produced against synthesized peptide derived from human MTIF3. AA range:69-118
Specificity:IF3 Polyclonal Antibody detects endogenous levels of IF3 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:MTIF3;DC38;Translation initiation factor IF-3; mitochondrial;IF-3(Mt);IF-3Mt;IF3(mt);IF3mt
Observed Band(KD):30kD
Background: This gene encodes a translation initiation factor that is involved in mitochondrial protein synthesis. Polymorphism in this gene is associated with the onset of Parkinson's disease. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Oct 2009],
Function:function:IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins.,similarity:Belongs to the IF-3 family.,
Subcellular Location:Mitochondrion .
Expression: Cervix,Colon,Dendritic cell,Melanocyte,