Target:SYFB
Fields:Aminoacyl-tRNA biosynthesis
Gene Name:FARSB FARSLB FRSB HSPC173
Protein Name:Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS)
Human Gene Id:10056
Human Swiss Prot No:Q9NSD9
Mouse Swiss Prot No:Q9WUA2
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:SYFB Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):64kD
Background: This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],
Function:catalytic activity:ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).,similarity:Belongs to the phenylalanyl-tRNA synthetase beta chain family. Type 2 subfamily.,subunit:Tetramer of two alpha and two beta chains.,
Subcellular Location:Cytoplasm .
Expression: Lung,Testis,Umbilical cord blood,