Target：StIp1

Gene Name：ELP2

Protein Name：Elongator complex protein 2

Human Gene Id：55250

Human Swiss Prot No：Q6IA86

Mouse Swiss Prot No：Q91WG4

Immunogen：The antiserum was produced against synthesized peptide derived from human ELP2. AA range:771-820

Specificity：StIp1 Polyclonal Antibody detects endogenous levels of StIp1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ELP2;STATIP1;Elongator complex protein 2;ELP2;SHINC-2;STAT3-interacting protein 1;StIP1

Observed Band(KD)：93kD

Background： The protein encoded by this gene is a core subunit of the elongator complex, a histone acetyltransferase complex that associates with RNA polymerase II. In addition to histone acetylation, the encoded protein effects transcriptional elongation and may help remodel chromatin. [provided by RefSeq, May 2016],

Function：function:Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.,function:Regulates the ligand-dependent activation of STAT3.,similarity:Belongs to the WD repeat ELP2 family.,similarity:Contains 14 WD repeats.,subunit:Component of the RNA polymerase II elongator complex (Elongator), which consists of IKBKAP/ELP1, STIP1/ELP2, ELP3, ELP4, and two yet unidentified proteins, p30 and p38. Elongator associates with the C-terminal domain (CTD) of Pol II largest subunit. Interacts with STAT3 and JAKs.,

Subcellular Location：Cytoplasm . Nucleus .

Expression： Hematopoietic,Liver,Ovary,Uterus,