Target：STEAP1

Fields：Mineral absorption

Gene Name：STEAP1

Protein Name：Metalloreductase STEAP1

Human Gene Id：26872

Human Swiss Prot No：Q9UHE8

Mouse Swiss Prot No：Q9CWR7

Immunogen：The antiserum was produced against synthesized peptide derived from human STEAP1. AA range:31-80

Specificity：STEAP1 Polyclonal Antibody detects endogenous levels of STEAP1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：STEAP1;PRSS24;STEAP;Metalloreductase STEAP1;Six-transmembrane epithelial antigen of prostate 1

Observed Band(KD)：36kD

Background： This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions. [provided by RefSeq, Jul 2008],

Function：cofactor:FAD.,function:Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor.,similarity:Belongs to the STEAP family.,similarity:Contains 1 ferric oxidoreductase domain.,tissue specificity:Ubiquitously expressed. Highly expressed in prostate tumors.,

Subcellular Location：Endosome membrane ; Multi-pass membrane protein .

Expression：Ubiquitously expressed. Highly expressed in prostate tumors.