Target：HuB/D

Gene Name：ELAVL2/ELAVL4

Protein Name：ELAV-like protein 2/ELAV-like protein 4

Human Gene Id：1993/1996

Human Swiss Prot No：Q12926/P26378

Mouse Gene Id：15569/15572

Rat Gene Id：432358

Rat Swiss Prot No：Q8CH84/O09032

Immunogen：The antiserum was produced against synthesized peptide derived from human ELAV2/4. AA range:61-110

Specificity：HuB/D Polyclonal Antibody detects endogenous levels of HuB/D protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ELAVL2;HUB;ELAV-like protein 2;ELAV-like neuronal protein 1;Hu-antigen B;HuB;Nervous system-specific RNA-binding protein Hel-N1;ELAVL4;HUD;PNEM;ELAV-like protein 4;Hu-antigen D;HuD;Paraneoplastic encephalomyelitis antigen HuD

Observed Band(KD)：40kD

Background：ELAV like RNA binding protein 2(ELAVL2) Homo sapiens The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],

Function：function:Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.,similarity:Belongs to the RRM elav family.,similarity:Contains 3 RRM (RNA recognition motif) domains.,tissue specificity:Brain; neural-specific.,

Subcellular Location：nucleoplasm,

Expression：Brain; neural-specific.