Target：SSTR4

Fields：Neuroactive ligand-receptor interaction

Gene Name：SSTR4

Protein Name：Somatostatin receptor type 4

Human Gene Id：6754

Human Swiss Prot No：P31391

Mouse Swiss Prot No：P49660

Rat Gene Id：25555

Rat Swiss Prot No：P30937

Immunogen：The antiserum was produced against synthesized peptide derived from human SSTR4. AA range:155-204

Specificity：SSTR4 Polyclonal Antibody detects endogenous levels of SSTR4 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SSTR4;Somatostatin receptor type 4;SS-4-R;SS4-R;SS4R

Observed Band(KD)：42kD

Background： Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR4 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in fetal and adult brain and lung. [provided by RefSeq, Jul 2008],

Function：function:Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Specifically expressed in fetal and adult brain, lung tissue, stomach, and in lesser quantities in the kidney, pituitary and adrenals.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression：Specifically expressed in fetal and adult brain, lung tissue, stomach, and in lesser quantities in the kidney, pituitary and adrenals.