Target：SRp55

Fields：Spliceosome;Herpes simplex virus 1 infection

Gene Name：SRSF6

Protein Name：Serine/arginine-rich splicing factor 6

Human Gene Id：6431

Human Swiss Prot No：Q13247

Immunogen：Synthesized peptide derived from SRp55 . at AA range: 30-110

Specificity：SRp55 Polyclonal Antibody detects endogenous levels of SRp55 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SRSF6;SFRS6;SRP55;Serine/arginine-rich splicing factor 6;Pre-mRNA-splicing factor SRP55;Splicing factor; arginine/serine-rich 6

Molecular Weight(Da)：40kD

Background： The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. Alternative splicing results in multiple transcript variants. In addition, two pseudogenes, one on chromosome 17 and the other on the X chromosome, have been found for this gene.[provided by RefSeq, Sep 2010],

Function：function:Plays a role in constitutive splicing and can modulate the selection of alternative splice sites.,PTM:Extensively phosphorylated on serine residues in the RS domain.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 2 RRM (RNA recognition motif) domains.,subunit:Binds SFRS12.,

Subcellular Location：Nucleus . Nucleus speckle .

Expression： Brain,Colon,Epithelium,Placenta,