Target：SR-5A

Fields：Calcium signaling pathway;Neuroactive ligand-receptor interaction;Serotonergic synapse

Gene Name：HTR5A

Protein Name：5-hydroxytryptamine receptor 5A

Human Gene Id：3361

Human Swiss Prot No：P47898

Mouse Swiss Prot No：P30966

Immunogen：The antiserum was produced against synthesized peptide derived from human HTR5A. AA range:15-64

Specificity：SR-5A Polyclonal Antibody detects endogenous levels of SR-5A protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：HTR5A;5-hydroxytryptamine receptor 5A;5-HT-5;5-HT-5A;5-HT5A;Serotonin receptor 5A

Observed Band(KD)：36kD

Background： The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008],

Function：function:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins.,similarity:Belongs to the G-protein coupled receptor 1 family.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression： Brain,Cerebellum,