Target：HSP76

Fields：Spliceosome;MAPK signaling pathway;Protein processing in endoplasmic reticulum;Endocytosis;Longevity regulating pathway - multiple species;Antigen processing and presentation;Estrogen signaling pathway;Prion disease;Legionellosis;Toxoplasmosis;Measles;Lipid and atherosclerosis

Gene Name：HSPA6 HSP70B'

Protein Name：Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B')

Human Gene Id：3310

Human Swiss Prot No：P17066

Immunogen：Synthesized peptide derived from human protein . at AA range: 200-280

Specificity：HSP76 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：70kD

Background：caution:Could be the product of a pseudogene.,function:In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.,induction:Only at higher temperatures, and no basal expression.,similarity:Belongs to the heat shock protein 70 family.,

Function：caution:Could be the product of a pseudogene.,function:In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.,induction:Only at higher temperatures, and no basal expression.,similarity:Belongs to the heat shock protein 70 family.,

Subcellular Location：cytoplasm,centriole,cytosol,COP9 signalosome,extracellular exosome,blood microparticle,

Expression： Cerebellum,Lung,Ovary,Skin,