Target:HSP10
Gene Name:HSPE1
Protein Name:10 kDa heat shock protein mitochondrial
Human Gene Id:3336
Human Swiss Prot No:P61604
Mouse Gene Id:15528
Mouse Swiss Prot No:Q64433
Rat Swiss Prot No:P26772
Immunogen:The antiserum was produced against synthesized peptide derived from human HSP10. AA range:51-100
Specificity:HSP10 Polyclonal Antibody detects endogenous levels of HSP10 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:HSPE1;10 kDa heat shock protein; mitochondrial;Hsp10;10 kDa chaperonin;Chaperonin 10;CPN10;Early-pregnancy factor;EPF
Observed Band(KD):10kD
Background: This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.[provided by RefSeq, Feb 2011],
Function:function:Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.,induction:By stress.,mass spectrometry: PubMed:7912672,similarity:Belongs to the groES chaperonin family.,subunit:Homohexamer.,
Subcellular Location:Mitochondrion matrix.
Expression: B-cell lymphoma,Uterus,